Kelly O’Brien, PhD, BScPT, BSc
Department of Physical Therapy
160-500 University Ave
Toronto, Ontario, M5G 1V7
Kelly O’Brien is a physical therapist and clinical epidemiologist who holds a Canada Research Chair in Episodic Disability and Rehabilitation. She is an Associate Professor in the Department of Physical Therapy, cross-appointed with the Institute of Health Policy, Management and Evaluation (IHPME), Clinical Epidemiology and Health Care Research (CEHCR) and Rehabilitation Sciences Institutes (RSI) at the University of Toronto. Her research is focused on episodic disability and rehabilitation in the context of HIV and chronic disease. Kelly is also a founding member of the Canada-International HIV and Rehabilitation Research Collaborative (CIHRRC).
*indicates trainees; ^indicates senior author
*Dagenais M, Cheng D, Salbach NM, Brooks D, O’Brien KK^ [senior responsible author]. Wireless Physical Activity Monitor Use Among Adults Living with HIV: A Scoping Review. Rehabilitation Oncology. January 2019. 37(1):17-28. https://journals.lww.com/rehabonc/Fulltext/2019/01000/Wireless_Physical_Activity_Monitor_Use_Among.5.aspx
O’Brien KK, Solomon P, Ibáñez-Carrasco F, Chegwidden W, McDonnell E, Brown D, Harding R, Bergin C, Worthington C, Tattle S, Baxter L, Nayar A, Kietrys DM, Galantino ML, Yates T on behalf of the Canada- International HIV and Rehabilitation Research Collaborative. Evolution of an International Research Collaborative in HIV and Rehabilitation: Community Engaged Process, Lessons Learned, and Recommendations. Progress in Community Health Partnerships: Research, Education and Action. Winter. 2018;12(4):395-408. http://muse.jhu.edu/article/716648
O'Brien KK, Dagenais M, Solomon P, Worthington C, Chan Carusone S, Ibáñez-Carrasco F, Hanna S, Gahagan J, Baxter L, Robinson G, Gayle P, James D, Yates T. and the HIV, Health and Rehabilitation Survey (HHRS) Team. Use of Living Strategies among HIV+ persons in Canada: Comparison by age group using data from the HIV, Health and Rehabilitation Survey. Journal of the International Association of Providers of AIDS Care (JIAPAC). May 10, 2018; Volume 17; 1-16. http://journals.sagepub.com/doi/full/10.1177/2325958218774041
*deBoer H, *Andrews M, *Cudd S, *Leung E, *Petrie A, Chan Carusone S, O’Brien KK^ [senior responsible author]. Where and how does physical therapy fit? Integrating physical therapy into interprofessional HIV care. Disability and Rehabilitation. Published Online: 13-March-2018. Available at: https://www.tandfonline.com/eprint/IjP9hGjSMnzMcJWVpMut/full
*Vader K, *Simonik A, *Ellis D, *Kesbian D, *Leung P, Jachyra P, Chan Carusone S, O’Brien KK^[senior responsible author]. ‘Physical activity’ versus ‘exercise’ among people living with HIV: A qualitative study. International Journal of Therapy and Rehabilitation. 2017; 24:11, 473-482.
O’Brien KK, Tynan AM, Nixon SA, Glazier RH. Effectiveness of Progressive Resistive Exercise in the Context of HIV: Systematic Review and Meta-Analysis Using the Cochrane Collaboration Protocol. BMC Infectious Diseases. 2017 Apr 12;17(1):268. doi: 10.1186/s12879-017-2342-8. Available at: https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-017-2342-8
*Montgomery CA, *Henning KJ, *Kantarzhi SR, *Kideckel TB, *Yang CFM, O’Brien KK^ [senior responsible author]. Experiences participating in a community-based exercise programme from the perspective of people living with HIV: a qualitative study. BMJ Open 2017;7:e015861. doi:10.1136/bmjopen-2017-015861. http://bmjopen.bmj.com/content/7/4/e015861.
*Li A, *McCabe T, *Silverstein E, *Dragan S, Salbach NM, Zobeiry M, Beldick S, Godi C, O’Brien KK^ [senior responsible author]. Community-based exercise in the context of HIV: Factors to consider when developing and implementing community-based exercise programs for people living with HIV. Journal of the International Association of Providers of AIDS Care (JIAPAC). 2017; 16(3): 267-275. http://journals.sagepub.com/doi/full/10.1177/2325957416686836
O’Brien KK, Bayoumi AM, Solomon P, Tang A, Murzin K, Chan Carusone S, Zobeiry M, Nayar A, Davis AM. Evaluating a Community-Based Exercise Intervention with Adults Living with HIV: Protocol for an Interrupted Time Series Study. BMJ Open. 2016;6:e013618 doi:10.1136/bmjopen-2016-013618. http://bmjopen.bmj.com/content/6/10/e013618.full
O’Brien KK, Tynan AM, Nixon SA, Glazier RH. Effectiveness of Aerobic Exercise for Adults Living with HIV: Systematic Review and Meta-Analysis Using the Cochrane Collaboration Protocol. BMC Infectious Diseases. April 26, 2016, 16:182 doi:10.1186/s12879-016-1478-2.
*Simonik A, *Vader K, *Ellis D,* Kesbian D, *Leung P, Jachyra P, Chan Carusone S, O’Brien KK^ [senior responsible author]. Are you ready? Exploring readiness to engage in exercise among people living with HIV and multi-morbidity in Toronto, Canada: a qualitative study. BMJ Open 2016;6:e010029 doi:10.1136/bmjopen-2015-010029. http://bmjopen.bmj.com/content/6/3/e010029.full
O’Brien KK, Solomon P, Bergin C, O’Dea S, Iku N, Stratford P, Bayoumi AM. Reliability and validity of a new HIV-specific questionnaire with adults living with HIV in Canada and Ireland: the HIV Disability Questionnaire (HDQ). Health and Quality of Life Outcomes. 2015. 13:124. http://www.hqlo.com/content/13/1/124
O’Brien KK, Ibanez-Carrasco F, Solomon P, Harding R, Cattaneo J, Chegwidden W, Gahagan J, Baxter L, Worthington C, Gayle P, Merritt B, Baltzer-Turje R, Iku N, Zack E. Advancing research and practice in HIV and rehabilitation: a framework of research priorities in HIV, disability and rehabilitation. BMC Infectious Diseases. 2014, 14:3851 doi:10.1186/s12879-014-0724-8. http://www.biomedcentral.com/1471-2334/14/724
O’Brien KK, Solomon P, Bayoumi AM. Measuring Disability Experienced by Adults Living with HIV: Assessing Construct Validity of the HIV Disability Questionnaire using Confirmatory Factor Analysis. BMJ Open. September 1, 2014. BMJ Open 2014;4:e005456 doi:10.1136/bmjopen-2014-005456 http://bmjopen.bmj.com/content/4/8/e005456.full?keytype=ref&ijkey=AYbGCcRZ5qaxaIw
O’Brien KK, Solomon P, Trentham B, MacLachlan D, MacDermid J, Tynan AM, Baxter L, Casey A, Chegwidden W, Robinson G, Tran T, Wu J, Zack E. Evidence-informed recommendations for rehabilitation with older adults living with HIV: a knowledge synthesis. BMJ Open. May 2014;4:e04692. doi:10.1136/bmjopen-2013-004692. Available at: http://bmjopen.bmj.com/content/4/5/e004692.full.
O’Brien KK, Davis AM, Gardner S, Bayoumi AM, Rueda S, Hart T, Cooper C, Solomon P, Rourke S, Hanna S, and the OHTN Cohort Study Team. Relationships between dimensions of disability experienced by adults living with HIV: A structural equation model analysis. AIDS and Behavior. 2014 18:357–367. DOI: 10.1007/s10461-012-0363-2
Levac D, Colquhoun H, O’Brien KK. Scoping studies: advancing the methodology. Implementation Science. 2010, 5:69. http://www.implementationscience.com/content/5/1/69 *Highly Accessed*
O’Brien KK, Bayoumi AM, Strike C, Young N, King K, Davis AM. How do existing HIV-specific instruments measure up? Evaluating the ability of instruments to describe disability experienced by adults living with HIV. Health and Quality of Life Outcomes. 2010. 8:88. http://www.hqlo.com/content/8/1/88
O'Brien K, Nixon S, Tynan A-M, Glazier R. Aerobic exercise interventions for adults living with HIV/AIDS. Cochrane Database of Systematic Reviews 2010, Issue 8. Art. No.: CD001796. DOI: 10.1002/14651858.CD001796.pub3
O’Brien K, Wilkins A, Zack E, Solomon P. Scoping the field: Identifying key research priorities in HIV and rehabilitation. AIDS and Behavior. April 2010, 14:2. 448-58. DOI 10.1007/s10461-009-9528-z http://springerlink.com/content/n28462l513635112/fulltext.pdf
O’Brien K, Davis AM, Strike C, Young N, Bayoumi AM. Putting episodic disability into context: Factors that influence disability experienced by adults living with HIV. Journal of the International AIDS Society. November 2009, 12:30. doi:10.1186/1758-2652-12-30. http://www.jiasociety.org/content/12/1/30. **Highly accessed**
O’Brien K, Strike C, Davis AM, Young N, Bayoumi AM. Using exploratory focus groups to establish a sampling strategy to investigate disability experienced by adults living with HIV. Current HIV Research. Volume 7, Number 6, November 2009. 626-633
O’Brien K, Bayoumi AM, Strike C, Young N, Davis AM. Exploring disability from the perspective of adults living with HIV/AIDS: Development of a conceptual framework. Health and Quality of Life Outcomes. 2008; 6:76. http://www.hqlo.com/content/6/1/76
O’Brien K, Tynan MA, Nixon S, Glazier RH. Effects of Progressive Resistive Exercise in Adults Living with HIV/AIDS: Systematic Review and Meta-Analysis of Randomized Trials. AIDS Care. July 2008: 20(6): 631-653.
O’Brien K. Factor Analysis: An Overview in the Field of Measurement. Physiotherapy Canada. 2007; 59: 142-55.
Dr. Kelly O’Brien’s research is focused on episodic disability and rehabilitation in the context of HIV and chronic disease. Her Episodic Disability and Rehabilitation Research Program involves an international academic-clinical-community partnership of researchers, clinicians, people living with HIV, policy stakeholders and community organization representatives with expertise in HIV, chronic disease, disability and rehabilitation, measurement, exercise, health services research, knowledge translation, and community-engaged research.
Specific research interests include: measuring and modeling episodic disability from the perspective of adults living with HIV (Episodic Disability Framework), developing and assessing the properties of patient-reported outcomes (PROs) of disability (HIV Disability Questionnaire (HDQ)), and examining effectiveness of physical activity and exercise interventions among adults living with HIV (Community-Based Exercise Study). Methodological areas of interest include: measurement, structural equation modeling, implementation science, Rasch analysis, qualitative methods, survey research, and systematic reviews.
Kelly is a founding member of the Canada-International HIV and Rehabilitation Research Collaborative (CIHRRC) (http://cihrrc.hivandrehab.ca/), member of the Ontario HIV Treatment Network Cohort Study (OCS) Scientific Steering Committee, and member of the Board of Directors of the Toronto People With AIDS (PWA) Foundation.
Translating Exercise into the HIV Community (Community-Based Exercise Study – CBE Study): The primary aim of this study is to evaluate the translation of a community-based exercise (CBE) intervention for adults living with HIV within the community. The secondary aim is to assess the measurement properties of the HIV Disability Questionnaire (HDQ) with adults living with HIV. Data collection is complete and analysis is in progress. For more information on the study protocol go to: https://bmjopen.bmj.com/content/6/10/e013618
(Funding: Canadian Institutes of Health Research, HIV/AIDS Community-Based Research Program; CBR #139685)
Closing the Gap! Evaluating the Implementation of Physical Therapy and an HIV Disability Questionnaire (HDQ) in an interdisciplinary HIV community-based care setting
The aim of this study is to pilot the evaluation of the implementation of a physical therapy (PT) model of care while advancing the use of a patient-reported outcome measure (PROM) of disability in the clinical community with adults living with HIV. This mixed methods pilot study involves quantitative (chart review) and qualitative (interviews and focus groups) approaches with adults living with HIV accessing physical therapy, and health care providers in HIV care. This study is a collaboration with Casey House. Recruitment and data collection is in progress.
(Funding: Canadian Institutes of Health Research, HIV/AIDS Community-Based Research Program; CDE #156908)
Dr. Kelly O’Brien teaches in the MScPT Research Curriculum in the Department of Physical Therapy. She is co-coordinator of Unit 6 (Research and Program Evaluation for Physical Therapy Practice I) and teaches on topics that include evidence-based practice, measurement, qualitative research, and systematic reviews. She also lectures the Institute of Health Policy, Management and Evaluation (IHPME), Clinical Epidemiology and Health Care Research (CEHCR) Program on measurement.
Associate Professor - Department of Physical Therapy, University of Toronto
Associate Professor - Institute of Health Policy, Management and Evaluation (IHPME), University of Toronto
Associate Professor - Rehabilitation Sciences Institute (RSI), University of Toronto, Toronto, Ontario, Canada.
Assistant Clinical Professor - School of Rehabilitation Science, Faculty of Health Sciences, McMaster University
Adjunct Scholar - Faculty of Graduate Studies, Dalhousie University